Pirkko Härkönen Selected Research

Fibroblast Growth Factor 8

8/2014	Deficiency of ERβ and prostate tumorigenesis in FGF8b transgenic mice.
8/2010	Fibroblast growth factor 8 induced downregulation of thrombospondin 1 is mediated by the MEK/ERK and PI3K pathways in breast cancer cells.

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Pirkko Härkönen Research Topics

Disease

22	Neoplasms (Cancer) 04/2022 - 08/2002
16	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 08/2002
13	Breast Neoplasms (Breast Cancer) 01/2022 - 08/2002
6	Neoplasm Metastasis (Metastasis) 12/2016 - 07/2008
2	Atrophy 01/2016 - 03/2005
2	Carcinogenesis 08/2014 - 03/2014
2	Disease Progression 04/2013 - 05/2010
2	Lymphatic Metastasis 10/2009 - 07/2008
2	Osteosarcoma (Osteogenic Sarcoma) 07/2008 - 08/2002
1	Autoimmune Diseases (Autoimmune Disease) 08/2018
1	Prostatic Intraepithelial Neoplasia 07/2016
1	Dyspareunia 01/2016
1	Carcinoma (Carcinomatosis) 01/2015
1	Leukemia 01/2013
1	Hypoxia (Hypoxemia) 09/2012
1	Infections 07/2008

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 01/2015 - 02/2005
5	Hormones (Hormone)IBA 06/2020 - 10/2006
4	Small Interfering RNA (siRNA)IBA 12/2016 - 07/2008
4	Estrogen ReceptorsIBA 01/2013 - 02/2005
3	Pharmaceutical PreparationsIBA 08/2018 - 03/2014
3	CytokinesIBA 01/2016 - 07/2008
3	Estrogens (Estrogen)FDA Link 08/2014 - 02/2005
2	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2022 - 03/2014
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2016
2	Androgen Receptors (Androgen Receptor)IBA 06/2020 - 09/2014
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 07/2016 - 03/2014
2	OspemifeneIBA 01/2016 - 03/2005
2	Phosphotransferases (Kinase)IBA 01/2015 - 06/2007
2	LigandsIBA 01/2015 - 09/2012
2	Fibroblast Growth Factor 8IBA 08/2014 - 08/2010
2	Cyclin A1IBA 01/2013 - 07/2008
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2013 - 07/2008
2	Non-Receptor Type 6 Protein Tyrosine PhosphataseIBA 10/2010 - 05/2010
2	Messenger RNA (mRNA)IBA 07/2008 - 03/2007
2	Estrogen Receptor alphaIBA 07/2008 - 02/2005
1	N-Acetylneuraminic Acid (Sialic Acid)IBA 04/2022
1	Polystyrenes (Polystyrene)IBA 04/2022
1	Silicon Dioxide (Silica)FDA LinkGeneric 04/2022
1	Molecularly Imprinted PolymersIBA 04/2022
1	LectinsIBA 04/2022
1	CA-125 Antigen (CA 125 Antigen)IBA 01/2022
1	Glycoproteins (Glycoprotein)IBA 01/2022
1	Mucin-1 (CA 15-3 Antigen)IBA 01/2022
1	MucinsIBA 01/2022
1	Tumor Biomarkers (Tumor Markers)IBA 01/2022
1	Wheat Germ AgglutininsIBA 01/2022
1	Prostate-Specific Antigen (Semenogelase)IBA 06/2020
1	Keratins (Keratin)IBA 06/2020
1	Toll-Like Receptor 9IBA 12/2016
1	Diphosphonates (Bisphosphonates)IBA 12/2016
1	fibroblast growth factor 13IBA 07/2016
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2016
1	Selective Estrogen Receptor Modulators (SERM)IBA 01/2016
1	proto-oncogene proteins pimIBA 01/2015
1	Chemokine ReceptorsIBA 01/2015
1	Chemokine CXCL12IBA 01/2015
1	ISA-2011BIBA 09/2014
1	AndrogensIBA 03/2014
1	Vascular Endothelial Growth FactorsIBA 01/2013
1	CyclinsIBA 01/2013
1	Tissue Inhibitor of Metalloproteinase-3IBA 09/2012
1	A-Form DNA (A-DNA)IBA 09/2012
1	Cyclin D1IBA 12/2010
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 10/2010
1	Interleukin-6 (Interleukin 6)IBA 10/2010
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 08/2010
1	Thrombospondin 1IBA 08/2010
1	Vascular Endothelial Growth Factor CIBA 10/2009
1	Annexin A3IBA 12/2008
1	Wnt-5a ProteinIBA 10/2008
1	Foxy-5 peptideIBA 10/2008
1	Metalloproteases (Metalloproteinases)IBA 07/2008
1	Matrix Metalloproteinases (MMPs)IBA 07/2008
1	Complementary DNA (cDNA)IBA 07/2008
1	Estrogen Receptor betaIBA 07/2008
1	Etoposide (VP 16)FDA LinkGeneric 07/2008
1	OsteocalcinIBA 07/2008
1	Cathepsin KIBA 07/2008
1	Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric 01/2008
1	SteroidsIBA 01/2008
1	Cell Cycle ProteinsIBA 01/2008
1	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 06/2007
1	Tamoxifen FDA LinkGeneric 06/2007
1	Protein Isoforms (Isoforms)IBA 02/2005
1	Peptide Hydrolases (Proteases)FDA Link 02/2005
1	LipidsIBA 12/2004
1	atrinositolIBA 12/2004
1	Codon (Codons)IBA 02/2004
1	OligonucleotidesIBA 02/2004
1	Adenosine Triphosphate (ATP)IBA 08/2002
1	ThymidineIBA 08/2002
1	Methanol (Carbinol)IBA 08/2002
1	Complex MixturesIBA 08/2002

Therapy/Procedure

4	Prostatectomy (Retropubic Prostatectomy) 06/2020 - 05/2010
4	Therapeutics 01/2015 - 10/2008
2	Castration 04/2016 - 03/2014
1	Injections 10/2008
1	Mammaplasty (Breast Reconstruction) 01/2008
1	Drug Therapy (Chemotherapy) 06/2007